Applications of Machine Learning in Viral Disease Diagnosis

Viral diseases are common and natural in human it spreads from animals and other humans. It seeks to identify the proper, reliable, and effective disease detection as quickly as possible so that patients can receive the right care. It becomes vital for medical field searches to have assistance from other disciplines like statistics and computer science because this detection is frequently a challenging process. These fields must overcome the difficulty of learning novel, non-traditional methodologies. Because so many new techniques are being developed, a thorough overview must be given while avoiding some specifics. In order to do this, we suggest a thorough analysis of machine learning which is used for the diagnosis of viral diseases caused in humans as well as plans. Predictions are made which is not obvious at the first glance does machine learning will be more helpful in making decisions. The study focuses on the machine learning algorithms for diagnosis of viral diseases for early diagnosis and treatment of viral diseases with greater accuracy. The work helps the researchers and medical professionals for learning and to give treatment for determining the applications of different machine learning techniques run to evaluate the parameters. Through examination of various parameters new machine learning model is proposed understanding the applications of machine learning in viral disease diagnosis like imaging techniques, plant virus diagnosis and the solution for the problem, Covid 19 diagnosis. © 2023 Bharati Vidyapeeth, New Delhi.

GPnome-wide mutation/SNP analysis. biological characteristics, and Pan-Inaia prevalence of SARS-CoV-2 variants or concern

The origin of COVID-19 pandemic, caused by SARS-CoV-2, was traced to Wuhan, China. Thereafter, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolved into various variants owing to genome-wide mutations, causing emergence of multiple variants, including Variant of Interest and Variant of Concern. Here, we discuss genomic architecture of SARS-CoV-2, as well as its multiple variantsalpha, beta, gamma, and delta, along with their biological properties, such as transmissibility, reduction in antibody-mediated neutralization, virulence, disease severity, vaccine effectiveness, and the prevalence across the India vis-a-vis world. Our data on VOC, pooled from the Global Initiative on Sharing All Influenza Data up to 31 October 2021, shows around 89% prevalence of delta VOC across various Indian States. Whereas alpha, beta, and gamma variants show 10.44%, 0.57%, and 0.11% prevalence, respectively. Compared with global scale, the reported Indian prevalence of alpha, beta, gamma, and delta are 0.40%, 0.63%, 0.04%, and 1.7%, respectively. Furthermore, prevalent vaccines of various natures show significantly reduced effectiveness against these VOCs, necessitating urgent need for development of effective prophylactic vaccines and potential therapy to contain the pandemic.

Genome-wide mutation/SNP analysis, biological characteristics, and Pan-India prevalence of SARS-CoV-2 Variants of Concern

The origin of COVID-19 pandemic, caused by SARS-CoV-2, was traced to Wuhan, China. Thereafter, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolved into various variants owing to genome-wide mutations, causing emergence of multiple variants, including Variant of Interest and Variant of Concern. Here, we discuss genomic architecture of SARS-CoV-2, as well as its multiple variants-alpha, beta, gamma, and delta, along with their biological properties, such as transmissibility, reduction in antibody-mediated neutralization, virulence, disease severity, vaccine effectiveness, and the prevalence across the India vis-à-vis world. Our data on VOC, pooled from the Global Initiative on Sharing All Influenza Data up to 31 October 2021, shows around 89% prevalence of delta VOC across various Indian States. Whereas alpha, beta, and gamma variants show 10.44%, 0.57%, and 0.11% prevalence, respectively. Compared with global scale, the reported Indian prevalence of alpha, beta, gamma, and delta are 0.40%, 0.63%, 0.04%, and 1.7%, respectively. Furthermore, prevalent vaccines of various natures show significantly reduced effectiveness against these VOCs, necessitating urgent need for development of effective prophylactic vaccines and potential therapy to contain the pandemic. © ScienceIn Publishing.